(4-Aminopyridine)–PLGA–PEG as a Novel Thermosensitive and Locally Injectable Treatment for Acute Peripheral Nerve Injury

作者: John C. Elfar , John P. Hegarty , Daniele Parisi , M A Hassan Talukder , Prem Kumar Govindappa

DOI: 10.1021/ACSABM.0C01566

关键词: 4-AminopyridineAnesthesiaPEG ratioCrush injuryPLGAMedicineAmputationSciatic nervePeripheral nerve injuryPlga peg

摘要: Traumatic peripheral nerve injury (TPNI) represents a major medical problem that results in loss of motor and sensory function, severe cases, limb paralysis amputation. To date, there ar...

参考文章(60)
Keith C Hayes, Fampridine-SR for multiple sclerosis and spinal cord injury. Expert Review of Neurotherapeutics. ,vol. 7, pp. 453- 461 ,(2007) , 10.1586/14737175.7.5.453
Keith C. Hayes, The Use of 4-Aminopyridine (Fampridine) in Demyelinating Disorders CNS Drug Reviews. ,vol. 10, pp. 295- 316 ,(2006) , 10.1111/J.1527-3458.2004.TB00029.X
F. K. Sanders, D. Whitteridge, Conduction velocity and myelin thickness in regenerating nerve fibres The Journal of Physiology. ,vol. 105, pp. 152- 174 ,(1946) , 10.1113/JPHYSIOL.1946.SP004160
Christopher A. Taylor, Diane Braza, J Bradford Rice, Timothy Dillingham, The incidence of peripheral nerve injury in extremity trauma. American Journal of Physical Medicine & Rehabilitation. ,vol. 87, pp. 381- 385 ,(2008) , 10.1097/PHM.0B013E31815E6370
Quansheng Chen, Yu Wang, Zhiyong Lu, Yujun Feng, Thermoviscosifying polymer used for enhanced oil recovery: rheological behaviors and core flooding test Polymer Bulletin. ,vol. 70, pp. 391- 401 ,(2013) , 10.1007/S00289-012-0798-7
John C Elfar, Justin A Jacobson, J Edward Puzas, Randy N Rosier, Michael J Zuscik, Erythropoietin accelerates functional recovery after peripheral nerve injury. Journal of Bone and Joint Surgery, American Volume. ,vol. 90, pp. 1644- 1653 ,(2008) , 10.2106/JBJS.G.00557
Kalpana S Paudel, Mikolaj Milewski, Courtney L Swadley, Nicole K Brogden, Priyanka Ghosh, Audra L Stinchcomb, Challenges and opportunities in dermal/transdermal delivery Therapeutic Delivery. ,vol. 1, pp. 109- 131 ,(2010) , 10.4155/TDE.10.16
Genghis E. Niver, Asif M. Ilyas, Management of Radial Nerve Palsy Following Fractures of the Humerus Orthopedic Clinics of North America. ,vol. 44, pp. 419- 424 ,(2013) , 10.1016/J.OCL.2013.03.012
Julius Bishop, David Ring, Management of Radial Nerve Palsy Associated With Humeral Shaft Fracture: A Decision Analysis Model The Journal of Hand Surgery. ,vol. 34, pp. 991- 996.e1 ,(2009) , 10.1016/J.JHSA.2008.12.029