作者: RA Krzyzek , SL Watts , DL Anderson , AJ Faras , F Pass
DOI: 10.1128/JVI.36.1.236-244.1980
关键词: Hpv types 、 Southern blot 、 Papillomaviridae 、 Virus 、 Virology 、 Nucleic acid thermodynamics 、 Human papillomavirus 、 Molecular biology 、 Biology 、 Staining 、 Hpv testing 、 Immunology 、 Insect Science 、 Microbiology
摘要: Anogenital warts from 26 patients were examined for the presence of human papillomavirus (HPV). Although no whole, intact virus could be identified, varying amounts nonintegrated HPV DNA detected in 18 tissue specimens (70%) by employing both an agarose gel-ethidium bromide staining method and Southern blot hybridization procedure. When analysis was performed under stringent conditions, six anogenital observed to contain genomic sequences related either cutaneous viruses type 1 (HPV-1) or HPV-2. In 12 samples lacking sequence homology HPV-1 HPV-2 HPV-related when less indicating that distinct is also associated with these lesions. This appeared other characterized types HPV. These data indicate at least three HPVs are wart disease.