Different trends in antibiotic resistance rates at a university teaching hospital
作者： M. SöUrberg , A. Farra , U. RansjöU , B. GÁRrdlund , M. Rylander
DOI: 10.1046/J.1469-0691.2003.00545.X
关键词: Intensive care 、 Imipenem 、 Pediatrics 、 Drug resistance 、 Antibiotic resistance 、 Internal medicine 、 Antibacterial agent 、 Ampicillin 、 Cefuroxime 、 Ciprofloxacin 、 Medicine
摘要: Objectives To investigate long-term trends in antibiotic resistance of common bacterial species isolated at a university hospital and its intensive care units (ICUs). Methods Levels pathogens were investigated the Karolinska Hospital during 12-year period 1988-99. Resistance rates analyzed for entire hospital, as well ICUs combined. Results At Hospital, we found increased ciprofloxacin among Escherichia coli isolates, from 0% 1991 to 11% 1999. In ICUs, corresponding increase was 4.8% same period. Co-trimoxazole levels 7.5% 14%, with lower ICUs. For ampicillin, cefuroxime, gentamicin, similar whole Among Pseudomonas aeruginosa imipenem higher ciprofloxacin, 2.5% 13% 1999 figures Conclusion The still generally low, but increasing some antibiotic-microbe combinations. results emphasize importance including all sectors surveillance studies, also value long periods.
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