The intervention of antioxidant therapy on platelet adhesion and immunomodulation in experimental physical stress.
作者： Manuela Ciocoiu , Manuela Ciocoiu , Magda M Badescu , Elena C Lupusoru
DOI: 10.1080/10715760701416434
关键词: Platelet adhesiveness 、 Malondialdehyde 、 Oxidative stress 、 Phagocytosis 、 Vitamin E 、 Antioxidant 、 Pharmacology 、 Reactive oxygen species 、 Chemistry 、 Diminution 、 Immunology
摘要: During effort overstress the reactive oxygen species act chiefly on unsaturated lipids, inducing formation of certain peroxidation products. We have investigated malondialdehide (MDA), platelet adhesion index, and immunological activation parameters during administration vitamins E C. Biochemical measurements were performed erythrocytes heart homogenate. In vitamin supplemented group, index was constantly correlated with MDA level (p < 0.001). There is a protecting effect concerning oxidative stress in animals pretreated C, which expressed through diminution quantity both erythrocyte heart. The physical required by swimming led to decrease NBT test values activity serum complement. steady overstress, due its antioxidant properties, causes progressive adhesion.
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