作者: J. C. Hutton
DOI: 10.1007/BF00265542
关键词: Organelle 、 Granule (cell biology) 、 Chromogranin A 、 Biology 、 Intracellular organelle 、 B cell 、 Autocrine signalling 、 Insulin 、 Biochemistry 、 Secretion
摘要: The insulin secretory granule of the pancreatic B cell is a complex intracellular organelle comprised many proteins with different catalytic activities and messenger functions. With advent tumour models cells application immunological molecular cloning techniques considerable progress has been made in recent years towards elucidation structure function these proteins. A number examples are selected here for review. Particular emphasis given to how quite interdependent this contributes co-ordination integration organelle's biological