Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia

作者: Tadashi Yoshida , A. Michael Tabony , Sarah Galvez , William E. Mitch , Yusuke Higashi

DOI: 10.1016/J.BIOCEL.2013.05.035

关键词: EndocrinologyAngiotensin IICachexiaMyostatinEnd stage renal diseaseInternal medicineOrexigenicMuscle atrophyMedicineSkeletal muscleAngiotensin-converting enzyme

摘要: … Ang II activates the ubiquitin–proteasome system via … only in patients with CHF and ESRD, but also in cancer cachexia. … disuse-induced skeletal muscle regeneration in aged mice not …

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