[Effects of Blending Oil of Lavender and Thyme on Oxidative Stress, Immunity, and Skin Condition in Atopic Dermatitis Induced Mice].

作者: Young Mi Seo , Seok Hee Jeong

DOI: 10.4040/JKAN.2015.45.3.367

关键词: Oxidative stressImmunoglobulin EAnalysis of varianceImmunologyEssential oilLavenderMedicineFactorial experimentAnimal scienceAtopic dermatitisImmunity

摘要: Purpose: The purpose of this study was to evaluate the effects essential oil on oxidative stress, immunity, and skin condition in atopic dermatitis (AD) induced mice. Methods: This a 3×3 factorial design. Factors were type (Lavender, Thyme, 2:1 mixture lavender thyme [blending oil]) treatment period (0 day, 7 days, 21 days). samples 45 mice with AD randomly assigned nine groups five per group. dependent variables such as superoxide radical, IgE, degranulated mast cells, epidermal thickness measured. Data collected from February April 2014. Descriptive statistics, One-way ANOVA, Two-way Tukey’s HSD test performed using SPSS WIN 20.0 program. Results: Dependent not statistically significantly different by three types (p >.05). Essential oils lavender, thyme, blending all effective reducing symptoms especially most effective. There significant differences periods <.001). interactions between <.01). For decreasing thickness, mixed should be applied for at least days. Otherwise reduce used Conclusion: These findings provide bases developing interventions patients manage their symptoms.

参考文章(29)
Helmut Sies, What is Oxidative Stress Springer, Boston, MA. pp. 1- 8 ,(2000) , 10.1007/978-1-4615-4649-8_1
Yong-Mi Lee, Experience of College Students on Suicide Attempts Journal of Korean Academy of Nursing. ,vol. 45, pp. 397- 411 ,(2015) , 10.4040/JKAN.2015.45.3.397
Sun Hee Han, Young Mi Seo, The Effect of Essential Oil on Atopic Dermatitis Model of NC/Nga Mice Journal of Korean Biological Nursing Science. ,vol. 16, pp. 219- 225 ,(2014) , 10.7586/JKBNS.2014.16.3.219
C. Karila, Dermatite atopique et allergie : quels liens ? Archives De Pediatrie. ,vol. 20, pp. 906- 909 ,(2013) , 10.1016/J.ARCPED.2013.04.011
Myun-Goo Kang, , Cha-Ho Jee, Repellent Effect of Camomile and Lavender Essential Oils against House Dust Mite in Bed Fabric Journal of Biomedical Research. ,vol. 13, pp. 21- 26 ,(2012) , 10.12729/JBR.2012.13.1.21
Peter M. Elias, Matthias Schmuth, Abnormal skin barrier in the etiopathogenesis of atopic dermatitis Current Allergy and Asthma Reports. ,vol. 9, pp. 265- 272 ,(2009) , 10.1007/S11882-009-0037-Y
Ji Won Oak, Hea Shoon Lee, Prevalence Rate and Factors Associated with Atopic Dermatitis among Korean Middle School Students Journal of Korean Academy of Nursing. ,vol. 42, pp. 992- 1000 ,(2012) , 10.4040/JKAN.2012.42.7.992