Supplementation with biscuits enriched with hesperidin and naringenin is associated with an improvement of the Metabolic Syndrome induced by a cafeteria diet in rats

摘要: Abstract Metabolic syndrome (MetS) has become a major public health concern. Because of their numerous health-promoting biological properties, polyphenols are potential candidates to ameliorate MetS and, recently, the incorporation these compounds into widely consumed foodstuffs emerged as strategy enhance intake. Therefore, we aimed assess beneficial effects biscuits enriched with citrus hesperidin and naringenin (HN) in rats that were fed either standard chow (STD) or an obesogenic cafeteria diet (CAF) for 16 weeks. The STD CAF groups supplemented control HN final 8 weeks study. CAF-fed developed MetS, characterized by obesity, insulin resistance, hypertension dyslipidemia. supplementation ameliorated resistance significantly reduced body weight, mesenteric adiposity, total cholesterol, LDL-C oxidative stress. Hence, may be promising functional food against MetS.