Preparation of N,N-p-phenylene bismethacryl amide as a novel cross-link agent for synthesis and characterization of the core-shell magnetic molecularly imprinted polymer nanoparticles.
作者： Saman Azodi-Deilami , Majid Abdouss , Davood Kordestani , Zahra Shariatinia
DOI: 10.1007/S10856-013-5118-8
关键词: Methacrylic acid 、 Materials science 、 Molecularly imprinted polymer 、 Polymer chemistry 、 Atom-transfer radical-polymerization 、 Methacryloyl chloride 、 Phenylene 、 Nanoparticle 、 Precipitation polymerization 、 Controlled release
摘要: Novel magnetic molecularly imprinted nanoparticles (MMIPs) using N,N-p-phenylene bismethacryl amide as a cross linker and super paramagnetic core–shell nanoparticle supporter for use in controlled release were prepared by precipitation polymerization. cross-linking agents synthesized the reaction of methacryloyl chloride with p-phenylenediamine. Then, Fe3O4 encapsulated SiO2 shell functionalized –CH=CH2 MMIPs further methacrylic acid functional monomer, agent betamethasone template. Magnetic non-MIPs also same synthesis procedure only without presence The obtained characterized transmission electron microscopy, Fourier transform infrared spectrum, X-ray diffraction, energy-dispersive spectroscopy, vibrating sample magnetometer. performance was assessed results indicated that MIPs had potential applications drug release.
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