作者: Yoshiaki Maeda , Olga V. Makhlynets , Hiroshi Matsui , Ivan V. Korendovych
DOI: 10.1146/ANNUREV-BIOENG-111215-024421
关键词: Computational biology 、 Nanotechnology 、 Chemistry 、 Rational design 、 Context (language use) 、 Catalytic function 、 Combinatorial design 、 Protein design
摘要: This review focuses on recent progress in noncomputational methods to introduce catalytic function into proteins, peptides, and peptide assemblies. We discuss various approaches creating activity classification of rational combinatorial classes. The section design covers the development short peptides oligomeric assemblies for natural unnatural reactions. describes advances discovery peptides. present future prospects these other new a broader context, including implications functional material design.