Biomechanical factors in diabetic foot disease

摘要: Although the risk of vascular disease is markedly increasedin diabetes [1], it combination altered vascularstatus and nerve damage that often leads to ulceration andamputation [2]. Important early studies by Brand col-leagues [3] focused on elevated stress in a deformed, neu-ropathic limb as causative factor tissue breakdownand this has been constant theme experimental andanalytical present day.The component normal foot (usually calledplantar pressure) typically available for study [4]and quantity associated with future ulcer-ation [5]. We have shown be useful, together withfoot shape, design pressure relieving footwear [6]and others derived quantities such gradi-ent indicate [7]. Recent plantar shearstress [8] reported higher neuropathic/control ratiosthan pressure, suggesting shear mayhave an important role damage.The measurement between thefootwear potentially very useful clinically [9]. If thepatient compliant use, stresses meas-ured using in-shoe techniques reflect influence ana-tomical structure, lower extremity function, lifestyle, andfootwear construction.Finite element modelling foot, some casesfootwear, explored number groups [10-12] provide estimates cannot bedirectly measured or perform simulations wouldbe onerous dangerous human subjects. Our ownrecent work directed towards development ofmore realistic soft models utilizing detailed defor-mation measurements structures [13] anattempt reduce burden mesh theuse morphing modify stock meshes.