Novel therapies for meningiomas.
作者： Patrick Y Wen , Jan Drappatz
DOI: 10.1586/14737175.6.10.1447
关键词: Radiation therapy 、 Medical physics 、 Radiosurgery 、 Targeted Molecular Therapy 、 Medicine 、 Intensive care medicine 、 Refractory 、 MEDLINE
摘要: Although advances in surgery, radiation therapy and stereotactic radiosurgery have significantly improved the treatment of meningiomas, there remains an important subset patients who remain refractory to conventional therapy. Treatment with chemotherapeutic agents such as hydroxyurea alpha-interferon has provided minimal benefit. In this review, role newly emerging novel therapies for a focus on targeted molecular agents, will be discussed.
expert-reviews.com参考文章(179)
Dora W. Hsu, Jimmy T. Efird, E. Tessa Hedley-Whyte, Progesterone and estrogen receptors in meningiomas: prognostic considerations Journal of Neurosurgery. ,vol. 86, pp. 113- 120 ,(1997) , 10.3171/JNS.1997.86.1.0113
G.-B.Van Setten, Lars Edström, Helena Stibler, Susan Rasmussen, Gregory Schultz, Levels of transforming growth factor alpha (TGF-a)in human cerebrospinal fluid International Journal of Developmental Neuroscience. ,vol. 17, pp. 131- 134 ,(1999) , 10.1016/S0736-5748(98)00069-0
Athanassios P. Kyritsis, Chemotherapy for meningiomas Journal of Neuro-oncology. ,vol. 29, pp. 269- 272 ,(1996) , 10.1007/BF00165657
Keith E. Friend, Robert Radinsky, Ian E. McCutcheon, Growth hormone receptor expression and function in meningiomas: effect of a specific receptor antagonist Journal of Neurosurgery. ,vol. 91, pp. 93- 99 ,(1999) , 10.3171/JNS.1999.91.1.0093
N Nathoo, GH Barnett, M Golubic, The eicosanoid cascade: possible role in gliomas and meningiomas Journal of Clinical Pathology. ,vol. 57, pp. 6- 13 ,(2004) , 10.1136/JCP.57.1.6
Keiro Ikeda, Yoshinaga Saeki, Charo Gonzalez-Agosti, Vijaya Ramesh, E. Antonio Chiocca, Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transfer. Journal of Neurosurgery. ,vol. 91, pp. 85- 92 ,(1999) , 10.3171/JNS.1999.91.1.0085
Anne Dutour, Ujendra Kumar, Rosemarie Panetta, L'Hovicine Ouafik, Federic Fina, Ramakrishnan Sasi, Yogesh C. Patel, Expression of somatostatin receptor subtypes in human brain tumors International Journal of Cancer. ,vol. 76, pp. 620- 627 ,(1998) , 10.1002/(SICI)1097-0215(19980529)76:5<620::AID-IJC2>3.0.CO;2-S
David Loven, Ruth Hardoff, Zvi Bar Sever, Adam P. Steinmetz, Michael Gornish, Zvi H. Rappaport, Eyal Fenig, Zvi Ram, Aaron Sulkes, Non-resectable slow-growing meningiomas treated by hydroxyurea. Journal of Neuro-oncology. ,vol. 67, pp. 221- 226 ,(2004) , 10.1023/B:NEON.0000021827.85754.8E
K.D. Zang, Meningioma: a cytogenetic model of a complex benign human tumor, including data on 394 karyotyped cases. Cytogenetic and Genome Research. ,vol. 93, pp. 207- 220 ,(2001) , 10.1159/000056986
Mark A. Watson, David H. Gutmann, Kelly Peterson, Michael R. Chicoine, Bette K. Kleinschmidt-DeMasters, Henry G. Brown, Arie Perry, Molecular characterization of human meningiomas by gene expression profiling using high-density oligonucleotide microarrays. American Journal of Pathology. ,vol. 161, pp. 665- 672 ,(2002) , 10.1016/S0002-9440(10)64222-8