A competence regulon in Streptococcus pneumoniae revealed by genomic analysis
作者： Elizabeth A. Campbell , Sook Yung Choi , H. Robert Masure
DOI: 10.1046/J.1365-2958.1998.00737.X
关键词: DNA 、 Transformation (genetics) 、 Biology 、 Locus (genetics) 、 Genetics 、 Genetic screen 、 Genome 、 DNA Transformation Competence 、 Streptococcus pneumoniae 、 Regulon
摘要: Transformation in bacteria is the uptake and incorporation of exogenous DNA into a cell's genome. Several species transform naturally during regulated state defined as competence. Genetic elements Streptococcus pneumoniae induced transformation were identified by combining genetic screen with genomic analysis. Six loci discovered that composed competence-induced regulon. These shared consensus promoter sequence encoded proteins, some which similar to proteins involved processing other bacteria. Each locus was competence essential for transformation.
sci-hub.se 参考文章(62)
Sanford Lacks, Integration Efficiency and Genetic Recombination in Pneumococcal Transformation Genetics. ,vol. 53, pp. 207- 235 ,(1966) , 10.1093/GENETICS/53.1.207
M Albano, D A Dubnau, Cloning and characterization of a cluster of linked Bacillus subtilis late competence mutations Journal of Bacteriology. ,vol. 171, pp. 5376- 5385 ,(1989) , 10.1128/JB.171.10.5376-5385.1989
Jeffrey H. Miller, A short course in bacterial genetics : a laboratory manual and handbook for Escherichia coli and related bacteria Published in <b>1992</b> in New York NY) by Cold Spring Harbor laboratory press. ,(1992)
D A Morrison, Transformation in pneumococcus: existence and properties of a complex involving donor deoxyribonucleate single strands in eclipse. Journal of Bacteriology. ,vol. 132, pp. 576- 583 ,(1977) , 10.1128/JB.132.2.576-583.1977
M Albano, R Breitling, D A Dubnau, Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon. Journal of Bacteriology. ,vol. 171, pp. 5386- 5404 ,(1989) , 10.1128/JB.171.10.5386-5404.1989
V. Méjean, J.P. Claverys, DNA processing during entry in transformation of Streptococcus pneumoniae. Journal of Biological Chemistry. ,vol. 268, pp. 5594- 5599 ,(1993) , 10.1016/S0021-9258(18)53362-7
C M Lovett, P E Love, R E Yasbin, Competence-specific induction of the Bacillus subtilis RecA protein analog: evidence for dual regulation of a recombination protein. Journal of Bacteriology. ,vol. 171, pp. 2318- 2322 ,(1989) , 10.1128/JB.171.5.2318-2322.1989
J Hahn, M Albano, D Dubnau, Isolation and characterization of Tn917lac-generated competence mutants of Bacillus subtilis. Journal of Bacteriology. ,vol. 169, pp. 3104- 3109 ,(1987) , 10.1128/JB.169.7.3104-3109.1987
V de Lorenzo, M Herrero, U Jakubzik, K N Timmis, Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in gram-negative eubacteria. Journal of Bacteriology. ,vol. 172, pp. 6568- 6572 ,(1990) , 10.1128/JB.172.11.6568-6572.1990
C. J. Bult, O. White, G. J. Olsen, L. Zhou, R. D. Fleischmann, G. G. Sutton, J. A. Blake, L. M. FitzGerald, R. A. Clayton, J. D. Gocayne, A. R. Kerlavage, B. A. Dougherty, J.-F. Tomb, M. D. Adams, C. I. Reich, R. Overbeek, E. F. Kirkness, K. G. Weinstock, J. M. Merrick, A. Glodek, J. L. Scott, N. S. M. Geoghagen, J. F. Weidman, J. L. Fuhrmann, D. Nguyen, T. R. Utterback, J. M. Kelley, J. D. Peterson, P. W. Sadow, M. C. Hanna, M. D. Cotton, K. M. Roberts, M. A. Hurst, B. P. Kaine, M. Borodovsky, H.-P. Klenk, C. M. Fraser, H. O. Smith, C. R. Woese, J. C. Venter, COMPLETE GENOME SEQUENCE OF THE METHANOGENIC ARCHAEON, $i(METHANOCOCCUS JANNASCHII) Science. ,vol. 273, pp. 1058- 1073 ,(1997) , 10.1126/SCIENCE.273.5278.1058