Bacterial mutation assays
作者： Errol Zeiger
DOI: 10.1007/978-1-62703-529-3_1
关键词: Data interpretation 、 Mutation (genetic algorithm) 、 Salmonella 、 Reverse mutation 、 Genetics 、 Mutagenicity Test 、 Pesticide 、 Histidine Metabolism 、 Tryptophan Metabolism 、 Biology
摘要: Bacterial mutagenicity tests, specifically the Salmonella and E. coli reverse mutation (Ames) test, are widely used usually required before a chemical, drug, pesticide, or food additive can be registered for use. The tests also environmental monitoring to detect mutagens in air water. Their use is based on showing that positive result test was highly predictive carcinogenesis. This chapter describes presents protocols their use, addresses data interpretation reporting.
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