C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease.
DOI: 10.1016/J.EXGER.2006.06.059
关键词: Disease 、 Human proteins 、 Alzheimer's disease 、 Neurodegeneration 、 Transgene 、 Biology 、 β amyloid 、 Caenorhabditis elegans 、 Pathology 、 Neuroscience
摘要: Caenorhabditis elegans has been used to model aspects of a number of age-associated neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Huntington’s diseases. …
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Mike Hutton, Corinne L. Lendon, Patrizia Rizzu, Matt Baker, Susanne Froelich, Henry Houlden, Stuart Pickering-Brown, Sumi Chakraverty, Adrian Isaacs, Andrew Grover, Jennifer Hackett, Jennifer Adamson, Sarah Lincoln, Dennis Dickson, Peter Davies, Ronald C. Petersen, Martijn Stevens, Esther de Graaff, Erwin Wauters, Jeltje van Baren, Marcel Hillebrand, Marijke Joosse, Jennifer M. Kwon, Petra Nowotny, Lien Kuei Che, Joanne Norton, John C. Morris, Lee A. Reed, John Trojanowski, Hans Basun, Lars Lannfelt, Michael Neystat, Stanley Fahn, Francis Dark, Tony Tannenberg, Peter R. Dodd, Nick Hayward, John B. J. Kwok, Peter R. Schofield, Athena Andreadis, Julie Snowden, David Craufurd, David Neary, Frank Owen, Ben A. Oostra, John Hardy, Alison Goate, John van Swieten, David Mann, Timothy Lynch, Peter Heutink, Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 Nature. ,vol. 393, pp. 702- 705 ,(1998) , 10.1038/31508
Christopher D Link, Andrew Taft, Vadim Kapulkin, Kyle Duke, Stuart Kim, Qing Fei, Douglas E Wood, Barbara G Sahagan, Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model. Neurobiology of Aging. ,vol. 24, pp. 397- 413 ,(2003) , 10.1016/S0197-4580(02)00224-5
Christopher D. Link, Virginia Fonte, Brian Hiester, John Yerg, Jmil Ferguson, Susan Csontos, Michael A. Silverman, Gretchen H. Stein, Conversion of Green Fluorescent Protein into a Toxic, Aggregation-prone Protein by C-terminal Addition of a Short Peptide Journal of Biological Chemistry. ,vol. 281, pp. 1808- 1816 ,(2006) , 10.1074/JBC.M505581200
Roberta Ricciarelli, Cristina d'Abramo, Sara Massone, Umberto Marinari, Maria Pronzato, Massimo Tabaton, Microarray Analysis in Alzheimer's Disease and Normal Aging Iubmb Life. ,vol. 56, pp. 349- 354 ,(2004) , 10.1080/15216540412331286002
M. G. Spillantini, J. R. Murrell, M. Goedert, M. R. Farlow, A. Klug, B. Ghetti, Mutation in the tau gene in familial multiple system tauopathy with presenile dementia Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 7737- 7741 ,(1998) , 10.1073/PNAS.95.13.7737
C. D. Link, Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 9368- 9372 ,(1995) , 10.1073/PNAS.92.20.9368
D. Quon, Y. Wang, R. Catalano, J. Marian Scardina, K. Murakami, B. Cordell, Formation of β-amyloid protein deposits in brains of transgenic mice Nature. ,vol. 352, pp. 239- 241 ,(1991) , 10.1038/352239A0
David S. Fay, Amy Fluet, Carolyn J. Johnson, Christopher D. Link, In Vivo Aggregation of β-Amyloid Peptide Variants Journal of Neurochemistry. ,vol. 71, pp. 1616- 1625 ,(2002) , 10.1046/J.1471-4159.1998.71041616.X
Alyce Finelli, Anju Kelkar, Ho-Juhn Song, Haidi Yang, Mary Konsolaki, A model for studying Alzheimer's Aβ42-induced toxicity in Drosophila melanogaster Molecular and Cellular Neuroscience. ,vol. 26, pp. 365- 375 ,(2004) , 10.1016/J.MCN.2004.03.001
Christopher D. Link, Carolyn J. Johnson, Virginia Fonte, Marie-Christine Paupard, David H. Hall, Scot Styren, Chester A. Mathis, William E. Klunk, Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34 Neurobiology of Aging. ,vol. 22, pp. 217- 226 ,(2001) , 10.1016/S0197-4580(00)00237-2