New inhibitors of tubulin polymerisation
作者： Erwin von Angerer
DOI: 10.1517/13543776.9.8.1069
关键词: Mode of action 、 Cryptophycins 、 Biochemistry 、 Pharmacology 、 Cryptophycin 、 Vinca 、 Biology 、 Combretastatin 、 Tubulin 、 Cryptophycin 52 、 Paclitaxel
摘要: … solid tumours by virtue of their anti-angiogenic activity or by inhibiting tubulin polymerisation … However, the increase of inhibitory activity on tubulin polymerisation was rather small and …
informahealthcare.com参考文章(46)
Vivien E. Prise, George R. Pettit, Graham G. Dark, Sally A. Hill, Dai J. Chaplin, Gillian M. Tozer, Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature Cancer Research. ,vol. 57, pp. 1829- 1834 ,(1997)
Kentaro Yoshimatsu, Nozomu Koyanagi, Atsumi Yamaguchi, Kyosuke Kitoh, Hiroshi Yoshino, Mechanism of action of E7010, an orally active sulfonamide antitumor agent : Inhibition of mitosis by binding to the colchicine site of tubulin Cancer Research. ,vol. 57, pp. 3208- 3213 ,(1997)
Nicola Gökbuget, Dieter Hoelzer, Vindesine in the treatment of leukaemia. Leukemia & Lymphoma. ,vol. 26, pp. 497- 506 ,(1997) , 10.3109/10428199709050886
Sudha Iyer, Dai J Chaplin, Dean S Rosenthal, A Hamid Boulares, L Y Li, Mark E Smulson, Induction of Apoptosis in Proliferating Human Endothelial Cells by the Tumor-specific Antiangiogenesis Agent Combretastatin A-4 Cancer Research. ,vol. 58, pp. 4510- 4514 ,(1998)
Ryuichi Shirai, Hisae Takayama, Asuka Nishikawa, Yukiko Koiso, Yuichi Hashimoto, Asymmetric synthesis of antimitotic combretadioxolane with potent antitumor activity against multi-drug resistant cells. Bioorganic & Medicinal Chemistry Letters. ,vol. 8, pp. 1997- 2000 ,(1998) , 10.1016/S0960-894X(98)00344-8
Robert Gastpar, Michael Goldbrunner, Doris Marko, Erwin von Angerer, Methoxy-Substituted 3-Formyl-2-phenylindoles Inhibit Tubulin Polymerization Journal of Medicinal Chemistry. ,vol. 41, pp. 4965- 4972 ,(1998) , 10.1021/JM980228L
Ernst ter Haar, Taxanes and other microtubule stabilising agents Expert Opinion on Therapeutic Patents. ,vol. 8, pp. 571- 586 ,(1998) , 10.1517/13543776.8.5.571
Dulal Panda, Mary Ann Jordan, Kevin Chin Chu, Leslie Wilson, Differential Effects of Vinblastine on Polymerization and Dynamics at Opposite Microtubule Ends Journal of Biological Chemistry. ,vol. 271, pp. 29807- 29812 ,(1996) , 10.1074/JBC.271.47.29807
Xiaoying Chen, Polly Pine, A.Merrill Knapp, Daniel Tusé, Keith R. Laderoute, Oncocidin A1: a novel tubulin-binding drug with antitumor activity against human breast and ovarian carcinoma xenografts in nude mice. Biochemical Pharmacology. ,vol. 56, pp. 623- 633 ,(1998) , 10.1016/S0006-2952(98)00210-X
Theodore Fotsis, Youming Zhang, Michael S. Pepper, Herman Adlercreutz, Roberto Montesano, Peter Paul Nawroth, Lothar Schweigerer, The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth Nature. ,vol. 368, pp. 237- 239 ,(1994) , 10.1038/368237A0