Vitamin-induced intracellular electrons are the mechanism for their well-known beneficial effects: a review.

作者: Nikola Getoff

DOI: 10.1016/J.NUT.2012.09.012

关键词: Aqueous solutionRadiolysisB vitaminsIntracellularSolvated electronMoleculeRadicalStereochemistryPhotochemistryChemistryVitamin

摘要: A new conception of the action mechanisms vitamins and some other compounds without a vitamin status is briefly presented. It based on results obtained through pulse radiolysis, molecular radiation biological investigations, in vitro studies. The data clearly show that antioxidant (C, E, β-carotene) B related possess capability to emit "solvated electrons" in aqueous solutions or polar media. In consequence, well-known effects are attributed emitted solvated electrons resulting free radicals rather than molecules per se, as generally accepted.

参考文章(54)
I. Gazdag, Gy. Toth, I. Szorady, X-RAY PROTECTION BY MEANS OF PANTOTHENIC ACID Progr. Biochem. Pharmacol.. ,(1965)
BENON H. J. BIELSKI, Chemistry of ascorbic acid radicals Adv. Chem. Ser.; (United States). ,vol. 200, ,(1982) , 10.1021/BA-1982-0200.CH004
Jan Grodkowski, P. Neta, Brian W. Carlson, Larry Miller, One-electron transfer reactions of the couple NAD.cntdot./NADH The Journal of Physical Chemistry. ,vol. 87, pp. 3135- 3138 ,(1983) , 10.1021/J100239A035
H. K. Biesalski, H. Weiss, P. Weber, J. Schrezenmeir, Vitamins: physiology, pathophysiology, therapy. Georg Thieme Verlag. ,(1997)
Utno LIa, Effects of pantethine on metabolism in myocardial mitochondria under the conditions of deep hypothermia Bulletin of Experimental Biology and Medicine. ,vol. 111, pp. 577- 578 ,(1991)
Lindsay Allen, Benjamin Caballero, Andrew Prentice, Encyclopedia of Human Nutrition ,(2012)