Nitric oxide synthase isoforms in the rat uterus: differential regulation during pregnancy and labour

摘要: Production of nitric oxide in the uterus is increased during pregnancy and decreased delivery. In this study isoform synthase which may be responsible for changes production was investigated relation to Monoclonal antibodies were used measure neuronal (NOS I), macrophage II) endothelial cell III) protein rat by densitometric scanning specific bands. Results show that : (1) NOS II concentrations substantially delivery, both at term preterm (induced RU486) ; (2) III present all stages examined but unchanged (3) I nonpregnant stage not The uterine delivery further confirmed Ca 2+ -independent, -dependent, activity. Therefore, an increase II, thus pregnancy, play a role maintaining quiescence.