Persimmon Fruit Tannin-Rich Fiber Reduces Cholesterol Levels in Humans
作者： Nobuki Gato , Akio Kadowaki , Natsumi Hashimoto , Shin-ichiro Yokoyama , Kenji Matsumoto
DOI: 10.1159/000343787
关键词: Endocrinology 、 Before Meals 、 Food material 、 Placebo group 、 Biochemistry 、 Chemistry 、 Diospyros kaki 、 Cholesterol 、 Internal medicine 、 Fiber 、 Tannin 、 Plasma total cholesterol 、 Nutrition and Dietetics 、 Medicine (miscellaneous)
摘要: Bile acid-binding agents are known to lower blood cholesterol levels and have been clinically used for the treatment of hypercholesterolemia. We previously showed that tannin-rich fiber from young persimmon (Diospyros kaki) fruits had bile properties. In this study, we performed a randomized, double-blind, placebo-controlled trial investigate hypocholesterolemic effects in humans. The subjects (n = 40, plasma total 180-259 mg/dl) were divided into 3 groups ingested cookie bars containing 0 g (placebo group, n 14), (low-dose 13), or 5 (high-dose 13) times daily before meals 12 weeks. Plasma decreased significantly low-dose (12 weeks, p < 0.005) high-dose (6 0.05; 0.001) groups. addition, low-density lipoprotein group 0.001). These improvements not accompanied by changes high-density triglyceride levels. Our findings indicate is useful food material treating
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