Chromosomal localization of complex and simple repeated human DNAs.

摘要: Complex repeating restriction multimers and a simple AT rich satellite isolated with Hoechst 33258 (<= 0.5% of the human genome) were localized by in situ hybridization to chromosomes. The complex repeats clustered at centromeres, consonant their integration tandem arrays these loci; sequences very prominent on chromosomes 7, 10 19, sites not previously identified any specific repeated sequence. labelled predominantly long arms Y chromosome. Although this did hybridize each other, contain detectable ribosomal sequences, both isolates additionally nucleolus organizing regions (NORs) acrocentric —The possible relationship DNAs, assignment chromosomal domains, is discussed.