作者: B Mester
关键词: Lymphoma 、 Population 、 Epidemiology 、 Diffuse large B-cell lymphoma 、 Occupational medicine 、 Follicular lymphoma 、 Medicine 、 Surgery 、 Demography 、 Logistic regression 、 Odds ratio 、 Public Health, Environmental and Occupational Health
摘要: Aims: To identify occupations suspected to be associated with malignant lymphoma and generate new hypotheses about occupational risks in a multicentre, population based case control study. Methods: Male female patients (n = 710) aged 18–80 years of age were prospectively recruited six study regions Germany. For each newly case, sex, region, matched was drawn from the registers. Odds ratios 95% confidence intervals for major industries calculated using conditional logistic regression analysis, adjusted smoking (in pack-years) alcohol consumption. Patients specific subentities additionally compared entire group unconditional analysis. Results: The following economic/industrial sectors positively lymphoma: food products, beverages, tobacco; paper publishing printing; metals. Chemicals; real estate, renting, business activities negatively diagnosis. authors observed an increased overall risk among architects; maids; farmers; glass formers; construction workers. Shoemaking leather goods making diagnosis (although on small numbers). In analysis subentities, Hodgkin’s significantly only rubber plastic products making; diffuse large B cell considerably metal processors; follicular showed highly significant increases several groups (medical, dental, veterinary workers; sales machinery fitters; electrical fitters); multiple myeloma particularly pronounced increase farmers as well agriculture animal husbandry Conclusions: results partly confirm previously defined risks. Occupational factors lymphomas might differ lymphoma.