Occupation and malignant lymphoma: a population based case control study in Germany

作者: B Mester

DOI: 10.1136/OEM.2005.020453

关键词: LymphomaPopulationEpidemiologyDiffuse large B-cell lymphomaOccupational medicineFollicular lymphomaMedicineSurgeryDemographyLogistic regressionOdds ratioPublic Health, Environmental and Occupational Health

摘要: Aims: To identify occupations suspected to be associated with malignant lymphoma and generate new hypotheses about occupational risks in a multicentre, population based case control study. Methods: Male female patients (n = 710) aged 18–80 years of age were prospectively recruited six study regions Germany. For each newly case, sex, region, matched was drawn from the registers. Odds ratios 95% confidence intervals for major industries calculated using conditional logistic regression analysis, adjusted smoking (in pack-years) alcohol consumption. Patients specific subentities additionally compared entire group unconditional analysis. Results: The following economic/industrial sectors positively lymphoma: food products, beverages, tobacco; paper publishing printing; metals. Chemicals; real estate, renting, business activities negatively diagnosis. authors observed an increased overall risk among architects; maids; farmers; glass formers; construction workers. Shoemaking leather goods making diagnosis (although on small numbers). In analysis subentities, Hodgkin’s significantly only rubber plastic products making; diffuse large B cell considerably metal processors; follicular showed highly significant increases several groups (medical, dental, veterinary workers; sales machinery fitters; electrical fitters); multiple myeloma particularly pronounced increase farmers as well agriculture animal husbandry Conclusions: results partly confirm previously defined risks. Occupational factors lymphomas might differ lymphoma.

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