Regulation of c-myc mRNA and Protein Levels During Activation of Normal Human B Cells
作者： Erlend B. Smeland , Tore Godal , Klaus Beiske , Rosemary Watt , Susan Pfeifer-Ohlsson
DOI: 10.1007/978-3-642-71562-4_43
关键词: Messenger RNA 、 Cell biology 、 Stimulation 、 Cell cycle 、 Cell cycle progression 、 Chemistry 、 Fibroblast 、 Oncogene 、 Cell culture 、 Cell
摘要: The myc oncogene has been implicated in the control of cellular proliferation both normal and neoplastic cells. Recently, several cell lines have shown to express c-myc mRNA protein throughout cycle (Thompson et al 1985; Hann Rabbitts 1985). However, systems triggering quiescent cells into G1 is accompanied by a marked burst mRNA, peaking few hours after stimulation (Kelly 1983; Goustin Smeland 1985a). This focused on possible function for product during induction competence respond progression growth factors acting G1. theory finds support studies fibroblast lines, where experimental manipulation levels was related (Armelin 1984; Kaczmarek In cases increased provoked an sensitivity action factors.
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