Multi-targeting by monotherapeutic antibacterials.
作者： Lynn L Silver
DOI: 10.1038/NRD2202
关键词: Biotechnology 、 Computer science 、 Risk analysis (engineering) 、 Multi targeting
摘要: Antibacterial discovery research has been driven, medically, commercially and intellectually, by the need for new therapeutics that are not subject to resistance mechanisms have evolved combat previous generations of antibacterial agents. This often equated with identification exploitation novel targets. But efforts towards development inhibitors targets proved frustrating. It might be 'good old targets' qualitatively different from crop all possible What learned existing can applied quest antibacterials?
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