Chapter 6 Talking to cells—cell membrane receptors and their modes of action

摘要: Publisher Summary This chapter focuses on the field of research that is signal transduction or cellular signaling. comprises a significant proportion world's total in life sciences. The cells tissues are under constant control hormones, neurotransmitters, and growth factors which telling to do this, that, stop doing instead. great majority these outside influences—agonists—are water-soluble. Most receptors transmembrane proteins but there some now recognized as having receptor function not span membrane—for example, those joined outer surface plasma membrane by glycosylphosphatidylinositol links. change structure following any agonist binding therefore causes conformation intracellular domains, it this generates signal.