Mortality as an adverse outcome of sarcopenia.

摘要: Sarcopenia has an important impact in elderly. Recently the European Working Group on Older People (EWGSOP) defined sarcopenia as loss of muscle mass plus low strength or physical performance. Lack clinical sounding outcomes (ie external validity), is one flaws this algorithm. The aim our study was to determine association and mortality a group Mexican A total 345 elderly were recruited Mexico City, followed up for three years. EWGSOP algorithm integrated by: gait speed, grip calf circumference. Other covariates assessed order test independent with mortality. Of subjects, 53.3% women; mean age 78.5 (SD 7) During year follow-up 43 (12.4%) subjects died. Age, cognition, ADL, IADL, health self-perception, ischemic heart disease associated bivariate analysis survival. Negative predictive value regarding 90%. Kaplan-Meier curves along their respective log-rank significant sarcopenia. components final Cox-regression multivariate model age, disease, ADL Adjusted HR 3.24 (CI 95% 1.55–6.78 p 0.002), IHD 5.07 1.89–13.59 0.001), self-perception 1.9–13.6 0.75 0.56–0.99 0.048) 2.39 1.05–5.43 0.037).