Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors
作者： Yong Liu , Jacqueline Ramírez , Mark J. Ratain
DOI: 10.1111/J.1365-2125.2011.03911.X
关键词: Nilotinib 、 Chemistry 、 Acetaminophen 、 Pharmacology 、 Tyrosine kinase 、 Dasatinib 、 Tyrosine-kinase inhibitor 、 Glucuronidation 、 Glucuronosyltransferase 、 Axitinib
摘要: … when paracetamol (acetaminophen) was co-administrated with some tyrosine kinase … a mechanism of potentiation of paracetamol hepatotoxicity. However, the effects of TKIs on …
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