Method for preparing 2-para octylphenyl ehtyl-2-amino propanediol

作者: Ma Qiming

DOI:

关键词: StyreneAlcoholOrganic chemistryChemistryHydrogenolysisSalt (chemistry)PropanediolEthylbenzeneElimination reactionDiethyl malonate

摘要: The invention provides a method to prepare compound method, including the steps: ethylbenzene and capryl chloride make Friedel-Crafts reaction generate p-capryl chloroethylbenzene; convert chloroethylbenzene under action of sodium iodide into iodoethylbenzene; iodoethylbenzene acetylamino diethyl malonate condense alkali 2-(p-capryl phenethyl)-2-acetylamino malonate; or makes elimination styrene, which together with condenses phenethyl)-2- is reduced 2-[4-(1-hydroxyoctyl) phenethyl-]2- propylene alcohol; other coumpound hydrogenolysis obtain 2-(p-octyl phenethyl)-acetylamino hydrolyzation then acidifies them salt, so as it. It also intermediate in above preparing course.

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