Integrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation
作者： Gwen E. Dressing , Carol A. Lange
DOI: 10.1016/J.STEROIDS.2008.12.001
关键词: Signal transduction 、 Progesterone receptor 、 Cell growth 、 Cyclin 、 Cell cycle 、 Cyclin-dependent kinase 、 Cancer 、 Cancer research 、 Biology 、 Breast disease
摘要: Multiple laboratories have investigated progesterone receptor (PR) involvement in breast cancer cell cycle progression. There is now a growing body of evidence demonstrating complex interactions between PR and regulatory proteins. Here we review the current literature linking to control discuss gaps knowledge. A more complete understanding relationships molecules may reveal additional avenues for prevention treatment steroid positive cancers.
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