The role of early adversity and recent life stress in depression severity in an outpatient sample
作者： Dominic Vogt , Sandra Waeldin , Dirk Hellhammer , Gunther Meinlschmidt
DOI: 10.1016/J.JPSYCHIRES.2016.08.007
关键词: Clinical psychology 、 Depression (differential diagnoses) 、 Injury prevention 、 Anxiety 、 Internal medicine 、 Mental health 、 Poison control 、 Suicide prevention 、 Medicine 、 Prenatal stress 、 Peri
摘要: Pre-, peri-, and postnatal stress have frequently been reported to be associated with negative health outcomes during adult life. However, it is unclear, if these factors independently predict mental in adulthood. We estimated potential associations between reports of pre-, depression severity outpatients (N = 473) diagnosed depression, anxiety or somatoform disorders by their family physician. retrospectively assessed measured as well recent life using questionnaires. First, we was predicted peri- and/or multiple regression models. Second, compared pre- levels patient subgroups different degrees severity, performing multilevel linear modeling. Third, analyzed an association current mediated stress. found no perinatal (all p > 0.05). Higher higher (p < 0.001). Patients moderately severe patients none minimal, mild p < 0.05). Mediation analysis revealed a significant indirect effect via the In for anxiety, disorders, but neither nor This
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