Peptide Receptor Radionuclide Therapy for the Treatment of Pancreatic Neuroendocrine Tumors: Recent Insights.

作者: Jason S Starr , Mohamad Bassam Sonbol , Timothy J Hobday , Akash Sharma , Ayse Tuba Kendi

DOI: 10.2147/OTT.S202867

关键词: Retrospective cohort studyPatient populationOncologyNeuroendocrine tumorsRandomized controlled trialPancreatic neuroendocrine tumorPeptide receptorRadionuclide therapyMedicineInternal medicine

摘要: Peptide receptor radionuclide therapy (PRRT) is a paradigm shifting approach to the treatment of neuroendocrine tumors. Although there are no prospective randomized trials directly studying PRRT in pancreatic tumors (panNETs), data suggest benefit this patient population. Collectively, data, consisting two and six retrospective studies, show median PFS ranging from 20 39 months OS 37 79 months. There ongoing (and upcoming) prospective, panNETs, which will provide further evidence support approach.

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