[Pneumocystis carinii pneumonia during therapy with 2-chlorodeoxyadenosine (2-CDA)].
作者： Tichelli A , Pless M , Speck B , Haberthür C , Gratwohl A
DOI:
关键词: Pneumonia 、 Purine analogue 、 Medicine 、 Immunology 、 Chronic lymphocytic leukemia 、 Pneumocystis carinii 、 Incidence (epidemiology) 、 Pneumocystis pneumonia 、 Chlorodeoxyadenosine 、 Acquired immunodeficiency syndrome (AIDS)
摘要: We report the case of a 70-year-old patient with B-cell chronic lymphocytic leukemia. During therapy new purine analog 2-chloro-deoxyadenosine (2-CDA) developed Pneumocystis carinii pneumonia (PCP). Although mechanism action 2-CDA suggests incidence opportunistic infections and therefore pneumocystis pneumonia, this is first PCP among 140 patients Swiss study 2-CDA. The described occurrence without acquired immunodeficiency syndrome discussed.
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