Stereoselective palladium-catalyzed carboaminoxylations of indoles with arylboronic acids and TEMPO.
作者： Sylvia Kirchberg , Roland Fröhlich , Armido Studer
关键词: Chemistry 、 Organic chemistry 、 Indole test 、 Catalysis 、 Palladium 、 Stereoselectivity 、 Enantioselective synthesis 、 Transition metal 、 Homogeneous catalysis
摘要: Indoles are not indolent: Various indoles react with arylboronic acids chemodivergently. C-H arylation of free indole and N-methylindole gives the corresponding C(2)-arylated A whereas N-acylated, N-benzoylated, N-Boc-protected provide arylcarboaminoxylated products B excellent diastereoselectivity in good to yields.
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