New drugs under development for Alzheimer's disease

作者: Lezanne Ooi , Kirubakaran Shanmugam , Mili Patel , Rachel Debono , Gerald Münch

DOI: 10.2217/EBO.11.368

关键词: Intensive care medicineUnderdevelopmentDiseaseMedicine

摘要:

参考文章(12)
G. Münch, S. R. Robinson, Alzheimer's vaccine: a cure as dangerous as the disease? Journal of Neural Transmission. ,vol. 109, pp. 537- 539 ,(2002) , 10.1007/S007020200044
E. Kickstein, S. Krauss, P. Thornhill, D. Rutschow, R. Zeller, J. Sharkey, R. Williamson, M. Fuchs, A. Kohler, H. Glossmann, R. Schneider, C. Sutherland, S. Schweiger, Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 21830- 21835 ,(2010) , 10.1073/PNAS.0912793107
ROMMY VON BERNHARDI, GIGLIOLA RAMIREZ, Microglia ­ astrocyte interaction in Alzheimer's disease: friends or foes for the nervous system? Biological Research. ,vol. 34, pp. 123- 128 ,(2001) , 10.4067/S0716-97602001000200017
Paul S Aisen, KL Davis, JD Berg, K Schafer, K Campbell, RG Thomas, MF Weiner, MR Farlow, M Sano, M Grundman, LJ Thal, Alzheimer’s Disease Cooperative Study, A randomized controlled trial of prednisone in Alzheimer’s disease Neurology. ,vol. 54, pp. 588- 588 ,(2000) , 10.1212/WNL.55.7.1067
S. Scharf, A. Mander, A. Ugoni, F. Vajda, N. Christophidis, A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer’s disease Neurology. ,vol. 53, pp. 197- 197 ,(1999) , 10.1212/WNL.53.1.197
J. Rogers, L. C. Kirby, S. R. Hempelman, D. L. Berry, P. L. McGeer, A. W. Kaszniak, J. Zalinski, M. Cofield, L. Mansukhani, P. Willson, F. Kogan, Clinical trial of indomethacin in Alzheimer's disease Neurology. ,vol. 43, pp. 1609- 1611 ,(1993) , 10.1212/WNL.43.8.1609
G Münch, Y Taneli, E Schraven, U Schindler, R Schinzel, D Palm, P Riederer, None, The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advanced glycosylation Journal of Neural Transmission - Parkinson's Disease and Dementia Section. ,vol. 8, pp. 193- 208 ,(1994) , 10.1007/BF02260940
Janet Van Eersel, Yazi D Ke, Xin Liu, Fabien Delerue, Jillian J Kril, Jürgen Götz, Lars M Ittner, Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 13888- 13893 ,(2010) , 10.1073/PNAS.1009038107
Edward Tobinick, Hyman Gross, Hart Cohen, Alan Weinberger, TNF-alpha modulation for treatment of Alzheimer's disease: a 6-month pilot study. MedGenMed : Medscape general medicine. ,vol. 8, pp. 25- 25 ,(2006)
K Hager, M Kenklies, J McAfoose, J Engel, G Münch, None, α-Lipoic acid as a new treatment option for Alzheimer’s disease — a 48 months follow-up analysis Neuropsychiatric Disorders An Integrative Approach. ,vol. 72, pp. 189- 193 ,(2007) , 10.1007/978-3-211-73574-9_24