Human RPA activates BLM’s bidirectional DNA unwinding from a nick
作者： Zhenheng Qin , Lulu Bi , Xi-Miao Hou , Siqi Zhang , Xia Zhang
DOI: 10.7554/ELIFE.54098
关键词: DNA unwinding 、 DNA 、 Replication protein A 、 Helicase 、 DNA repair 、 DNA replication 、 Structural biology 、 Gene 、 Cell biology
摘要: BLM is a multifunctional helicase that plays critical roles in maintaining genome stability. It processes distinct DNA substrates, but not nicked DNA, during many steps in DNA replication …
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