Solubility of solid carnosic acid in supercritical CO2 with ethanol as a co-solvent

摘要: Abstract The present study is devoted to the experimental measurement and thermodynamic modeling of solid carnosic acid solubility in supercritical CO 2  + ethanol as a co-solvent. Measurements were carried out at temperatures range 313.15 333.15 K, pressures ranging from 280 400 bar, different content modifier ethanol (from 0.7 10%). Group Contribution Associating Equation State (GCA-EoS) [H.P. Gros, S.B. Bottini, E.A. Brignole, High pressure phase equilibrium mixtures containing associating compounds gases, Fluid Phase Equilibria 139 (1997) 75–87] was applied this work represent data obtained. Due lack information literature about pure parameters, its volume, critical properties, sublimation estimated work. key step proved be introduction solute hard-sphere parameter Carnahan–Starling repulsive term model, which depends on both temperature pressure.