TBD-organocatalysed synthesis of pyrazolines.

作者： Olivier Mahé , Denis Frath , Isabelle Dez , Francis Marsais , Vincent Levacher

DOI: 10.1039/B911577C

关键词: Organic chemistry 、 Guanidine 、 Chemistry 、 Combinatorial chemistry 、 Amine alkylation

摘要: It was found that TBD, a cheap and commercially available guanidine, easily catalysed the synthesis of biologically important 3,5-diarylpyrazolines from chalcones acylhydrazines via selective secondary amine alkylation.

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