Chemical profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets seized in Hong Kong.

摘要: During 2000-2001, the Government Laboratory of Hong Kong received over 600,000 ecstasy tablets in more than 2,600 cases. Using GC-MS or FTIR, major amphetamine-type stimulants were identified, and samples categorized into four groups containing: (1) 3,4-methylenedioxymethamphetamine (MDMA), (2) methamphetamine (MA), (3) 3,4-methylenedioxyamphetamine (MDA), (4) amphetamine. Our study revealed that MDMA have made up 98 71% total examined 2000 2001, respectively. Among cases, 613 cases involving a 123,776 2001 randomly selected, their active ingredients, minor and/or impurities studied using HPLC. Based on chemical profiles, irrespective different physical characteristics, obtained seizures could be determined as to whether not they come from common origin. The detected also served excellent markers which plausible synthetic route(s) inferred. 3,4-methylenedioxyphenyl-2-propanone (MDP2P), 3,4-methylenedioxyphenyl-2-propanol (MDP), 3,4-methylenedioxy-N-methylbenzylamine (MDB), piperonal N-formyl-3,4-methylenedioxymethamphetamine (N-formyl-MDMA) most seized Kong. finding phosphate salt is intriguing. presumptive color test, spectroscopic data (FTIR/ESI-MS) percentage content purified MDMA, ratio was 1:1, suggesting compound dihydrogen [i.e. (HMDMA)H2PO4].