Models versus established knowledge in describing the functional morphology of the ventricular myocardium.

作者: Paul P. Lunkenheimer , Klaus Redmann , Peter Niederer , Peter Schmid , Morten Smerup

DOI: 10.1016/J.HFC.2008.02.012

关键词: InotropeAnatomyFunctional morphologyInternal medicineHeart failureVentricular myocardiumVentricular imbalanceMedicineMyocyteVentricular massPopulationCardiology

摘要: The myocytes comprising the ventricular mass are arranged so as to function in antagonistic fashion, walls having capacity generate both constrictive and dilatory forces. This dualistic activity is organized on basis of a site-specific morphologic pattern, permitting marked regional specificity for mural motion providing target therapy. Diseased regions can be removed surgically without danger jeopardizing remaining healthy segments. sensitivity intruding population positive negative inotropic medication markedly more pronounced than that prevailing tangentially aligned myocytes. asymmetrical action inotropes setting global imbalance promotes potential restore opposed actions.

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