Stellenwert von Digitalis in der Therapie der akuten und chronischen Herzinsuffizienz

摘要: Although supported by more than 200 years of experience and anecdotal clinical evidence, the efficacy digitalis in management heart failure has been questioned until past decade. The idea to improve contractility diseased myocardium with an inotropic agent is fundamental left ventricular dysfunction. majority trials published since 1980, most which examined patients mild moderate failure, indicate that alone or combination vasodilators may outcome particular those advanced symptoms poorer function. Aside from its action as drug pharmacology mechanisms influence peripheral circulation gained complexity within last years, raising other might be involved action. Particular for ACE inhibition multiple have conclusively demonstrated impact on survival morbidity congestive failure. Improvement measured terms fewer hospitalizations improvement receiving seems comparable beta-blockers additional diuretics inhibitors, entirely different approach treatment Despite initial hemodynamics it now appears there no benefit found