Evaluation of the performance of ultrasonography and 99mTc-sestamibi scintigraphy for primary hyperparathyroidism surgery.

摘要: Abstract Introduction Minimally invasive surgery has become the standard surgical attitude in primary hyperparathyroidism. It requires precise preoperative lesion localization. The aim of present study was to evaluate performance ultrasonography and 99mTc-sestamibi scintigraphy minimally for Materials methods A retrospective included all patients managed surgically hyperparathyroidism between January 2008 November 2017 University Hospital Brest (France). Two hundred seventy-three underwent scintigraphy. Results determined intrinsic (sensitivity specificity) extrinsic (positive negative predictive values) on per-patient per-gland analysis. Demographic, preoperative, interventional cure data were compared according results, distinguishing 3 patient groups: concordant n = 156, discordant n = 99, n = 18. On analysis, sensitivity 70% ultrasound, 74% 81% associated ultrasound-scintigraphy; positive values 89%, 91% 96%, respectively. Gland volume concomitant thyroid pathology rates differed significantly (both p = 0.003) imaging results groups. Conclusion ultrasound-99mTc-sestamibi-scintigraphy provided a value 96%. Combining two techniques reduced morbidity.