FcγRIIA and FcγRIIIB Are Required for Autoantibody-Induced Tissue Damage in Experimental Human Models of Bullous Pemphigoid
作者： Xinhua Yu , Karoline Holdorf , Brigitte Kasper , Detlef Zillikens , Ralf J. Ludwig
DOI: 10.1038/JID.2010.230
关键词: Autoantibody 、 Autoimmune disease 、 Tissue damage 、 Organ Culture Technique 、 Immunopathology 、 Pathology 、 Medicine 、 Immunology 、 Autoimmunity 、 GPI-Linked Proteins 、 Bullous pemphigoid
摘要:
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nature.com参考文章(13)
Kristin M. Leiferman, Kristin M. Leiferman, Walter Newman, Terry George, Leopoldo Borrego, Margot S. Peters, Luis Iglesias, Ellen A. Peterson, Bruno Maynard, Gerald J. Gleich, Deposition of eosinophil granule proteins precedes blister formation in bullous pemphigoid: Comparison with neutrophil and mast cell granule proteins American Journal of Pathology. ,vol. 148, pp. 897- 909 ,(1996)
Z Liu, G J Giudice, X Zhou, S J Swartz, J L Troy, J A Fairley, G O Till, L A Diaz, A major role for neutrophils in experimental bullous pemphigoid Journal of Clinical Investigation. ,vol. 100, pp. 1256- 1263 ,(1997) , 10.1172/JCI119639
Brigitte Kasper, Ernst Brandt, Silvia Bulfone-Paus, Frank Petersen, Platelet factor 4 (PF-4)-induced neutrophil adhesion is controlled by src-kinases, whereas PF-4-mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinase. Blood. ,vol. 103, pp. 1602- 1610 ,(2004) , 10.1182/BLOOD-2003-08-2802
Maria-Concetta Veri, Sergey Gorlatov, Hua Li, Steve Burke, Syd Johnson, Jeffrey Stavenhagen, Kathryn E. Stein, Ezio Bonvini, Scott Koenig, Monoclonal antibodies capable of discriminating the human inhibitory Fc?-receptor IIB (CD32B) from the activating Fc?-receptor IIA (CD32A): biochemical, biological and functional characterization Immunology. ,vol. 121, pp. 392- 404 ,(2007) , 10.1111/J.1365-2567.2007.02588.X
W. Ray Gammon, Carolyn C. Merritt, Daniel M. Lewis, W. Mitchell Sams, Jaime R. Carlo, Clayton E. Wheeler, An in Vitro Model of Immune Complex-mediated Basement Membrane Zone Separation Caused by Pemphigoid Antibodies, Leukocytes, and Complement Journal of Investigative Dermatology. ,vol. 78, pp. 285- 290 ,(1982) , 10.1111/1523-1747.EP12507222
Cassian Sitaru, Enno Schmidt, Steffen Petermann, Luminita S. Munteanu, Eva-B Bröcker, Detlef Zillikens, Autoantibodies to bullous pemphigoid antigen 180 induce dermal-epidermal separation in cryosections of human skin. Journal of Investigative Dermatology. ,vol. 118, pp. 664- 671 ,(2002) , 10.1046/J.1523-1747.2002.01720.X
Falk Nimmerjahn, Jeffrey V. Ravetch, Fcγ receptors as regulators of immune responses Nature Reviews Immunology. ,vol. 8, pp. 34- 47 ,(2008) , 10.1038/NRI2206
MT Chiriac, J Roesler, A Sindrilaru, K Scharffetter-Kochanek, D Zillikens, C Sitaru, NADPH oxidase is required for neutrophil-dependent autoantibody-induced tissue damage. The Journal of Pathology. ,vol. 212, pp. 56- 65 ,(2007) , 10.1002/PATH.2157
M Li, U Wirthmueller, J V Ravetch, Reconstitution of human Fc gamma RIII cell type specificity in transgenic mice. Journal of Experimental Medicine. ,vol. 183, pp. 1259- 1263 ,(1996) , 10.1084/JEM.183.3.1259
John J. Zone, Ted Taylor, Christopher Hull, Linda Schmidt, Laurence Meyer, IgE Basement Membrane Zone Antibodies Induce Eosinophil Infiltration and Histological Blisters in Engrafted Human Skin on SCID Mice Journal of Investigative Dermatology. ,vol. 127, pp. 1167- 1174 ,(2007) , 10.1038/SJ.JID.5700681