Surface-immobilized polyethylene oxide for bacterial repellence

作者: Neil P. Desai , Syed F.A. Hossainy , Jeffrey A. Hubbell

DOI: 10.1016/0142-9612(92)90160-P

关键词: Surface modificationAdhesionPolyethyleneBiomaterialNuclear chemistryStaphylococcus aureusMaterials scienceOrganic chemistryPolyethylene terephthalateStaphylococcus epidermidisBacteria

摘要: Polyethylene terephthalate films were surface-modified with polyethylene oxide (18,500 g/mol) using a solution technique described previously. These investigated for their resistance to bacterial adhesion. Three strains most commonly associated implant infections, Staphylococcus epidermidis, aureus and Pseudomonas aeruginosa, cultured in tryptic soya broth, human plasma serum on the polymeric substrates. Significant reductions (between 70 95%) adherent bacteria observed oxide-modified substrates compared untreated control terephthalate. Surface modification may reduce risk of implant-associated infections. Plasma fibrinogen was play an important role adhesion all three these species both materials. [on SciFinder (R)]

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