NATURAL KILLER CELLS IN THE MOUSE
作者： ROLF KIESSLING
DOI: 10.1016/B978-0-12-401660-6.50012-6
关键词: In vitro 、 Natural killer cell 、 Spleen 、 Cell fractionation 、 Molecular biology 、 Immunology 、 Lymphokine-activated killer cell 、 Biology 、 In vivo 、 Lymphoma 、 Cytolysis
摘要: Abstract Non-immune lymphocytes from some mouse strains can kill certain syngeneic, semisyngeneic and allogeneic lymphoma cells in a 51Cr release assay. The cytolytic activity was selective, but the specificity unknown. Spleen peripheral blood 1–2 month old mice yielded highest activity. nude were highly active. This natural killer cell (abbreviated NK) appeared to be small lymphocyte could not classified as T- or B-lymphocyte by various fractionation procedures. vitro genotype dependent. Genetic analysis revealed that responsible gene(s) dominant, with an H-2 linked factor(s). A high degree of concordance seen when compared vivo tumor resistance different genotypes, using Moloney virus induced lymphoma. Also same thymus independent.
sci-hub.st 参考文章(13)
A H Greenberg, J H Playfair, Spontaneously arising cytotoxicity to the P-815-Y mastocytoma in NZB mice. Clinical and Experimental Immunology. ,vol. 16, pp. 99- 109 ,(1974)
B. L. Batzing, R. W. Tennant, J. M. Yuhas, N. K. Clapp, M. J. Snodgrass, M. G. Hanna, Autogenous Immunity to Endogenous RNA Tumor Virus Antigens in Mice with a Low Natural Incidence of Lymphoma Cancer Research. ,vol. 32, pp. 2226- 2234 ,(1972)
Edward A. Boyse, Tadao Aoki, Lloyd J. Old, Occurrence of Natural Antibody to the G (Gross) Leukemia Antigen in Mice Cancer Research. ,vol. 26, pp. 1415- 1419 ,(1966)
R. C. Nowinski, S. L. Kaehler, Antibody to Leukemia Virus: Widespread Occurrence in Inbred Mice Science. ,vol. 185, pp. 869- 871 ,(1974) , 10.1126/SCIENCE.185.4154.869
R. Kiessling, Eva Klein, H. Pross, H. Wigzell, "Natural" killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell. European Journal of Immunology. ,vol. 5, pp. 117- 121 ,(1975) , 10.1002/EJI.1830050209
Ronald B. Herberman, Myrthel E. Nunn, Howard T. Holden, David H. Lavrin, Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells International Journal of Cancer. ,vol. 16, pp. 230- 239 ,(1975) , 10.1002/IJC.2910160205
MASUMI NOZAWA, RICHARD WEIL, RAWLE MCINTOSH, KEITH REEMTSMA, Is immunological surveillance not a cell-mediated immune function? Transplantation. ,vol. 17, pp. 135- 139 ,(1974) , 10.1097/00007890-197401000-00023
Gyözö G. Petrányi, Rolf Kiessling, George Klein, Genetic control of 'natural' killer lymphocytes in the mouse. Immunogenetics. ,vol. 2, pp. 53- 61 ,(1975) , 10.1007/BF01572274
M. B. A. Oldstone, T. Aoki, F. J. Dixon, The Antibody Response of Mice to Murine Leukemia Virus in Spontaneous Infection: Absence of Classical Immunologic Tolerance Proceedings of the National Academy of Sciences of the United States of America. ,vol. 69, pp. 134- 138 ,(1972) , 10.1073/PNAS.69.1.134
J. N. Ihle, M. Yurconic, M. G. Hanna, AUTOGENOUS IMMUNITY TO ENDOGENOUS RNA TUMOR VIRUS : RADIOIMMUNE PRECIPITATION ASSAY OF MOUSE SERUM ANTIBODY LEVELS Journal of Experimental Medicine. ,vol. 138, pp. 194- 208 ,(1973) , 10.1084/JEM.138.1.194