In vivo metabolism of ceramides in rat brain. Fatty acid replacement and esterification of ceramide.

作者: H Okabe , Y Kishimoto

DOI: 10.1016/S0021-9258(19)66935-8

关键词: ChemistrySphingosineSphingolipidBiochemistryChromatographyRat brainIn vivo metabolismCeramideFatty acid esterFatty acidSphingomyelin

摘要: … (a) Its R, value on TLC was identical to that of synthetic monostearoyl-2\r-palmitoyl D- erythro-… was recovered in the ceramide which, after TABLE III [I-â€-â€C]Palrmtoyl D-erythro-[l-â€lH]…

参考文章(47)
Yukihiro Shoyama, Yasuo Kishimoto, Invivo conversion of 3-ketoceramide to ceramide in rat liver Biochemical and Biophysical Research Communications. ,vol. 70, pp. 1035- 1041 ,(1976) , 10.1016/0006-291X(76)91006-8
F. B. Jungalwala, R. M. C. Dawson, The turnover of myelin phospholipids in the adult and developing rat brain. Biochemical Journal. ,vol. 123, pp. 683- 693 ,(1971) , 10.1042/BJ1230683
Peter E. Braun, Pierre Morell, Norman S. Radin, Synthesis of C18- and C20-Dihydrosphingosines, Ketodihydrosphingosines, and Ceramides by Microsomal Preparations from Mouse Brain Journal of Biological Chemistry. ,vol. 245, pp. 335- 341 ,(1970) , 10.1016/S0021-9258(18)63397-6
Pierre Morell, Norman S. Radin, Specificity in Ceramide Biosynthesis from Long Chain Bases and Various Fatty Acyl Coenzyme A's by Brain Microsomes Journal of Biological Chemistry. ,vol. 245, pp. 342- 350 ,(1970) , 10.1016/S0021-9258(18)63398-8
N.M. Neskovic, L.L. Sarlieve, P. Mandel, Brain UDPgalactose: Ceramide galactosyltransferase Biochimica et Biophysica Acta (BBA) - Enzymology. ,vol. 429, pp. 342- 351 ,(1976) , 10.1016/0005-2744(76)90282-5
Subhash Basu, Alan M. Schultz, Manju Basu, Saul Roseman, Enzymatic Synthesis of Galactocerebroside by a Galactosyltransferase from Embryonic Chicken Brain Journal of Biological Chemistry. ,vol. 246, pp. 4272- 4279 ,(1971) , 10.1016/S0021-9258(18)62081-2
Kiyoshi Tatsumi, Yasuo Kishimoto, Charles Hignite, Stereochemical aspects of synthetic and naturally occurring 2-hydroxy fatty acids Archives of Biochemistry and Biophysics. ,vol. 165, pp. 656- 664 ,(1974) , 10.1016/0003-9861(74)90294-X
M. David Ullman, Norman S. Radin, The Enzymatic Formation of Sphingomyelin from Ceramide and Lecithin in Mouse Liver Journal of Biological Chemistry. ,vol. 249, pp. 1506- 1512 ,(1974) , 10.1016/S0021-9258(19)42911-6