Antimicrobial activity and resistance selection of different bioglass S53P4 formulations against multidrug resistant strains.
作者： Lorenzo Drago , Elena De Vecchi , Monica Bortolin , Marco Toscano , Roberto Mattina
DOI: 10.2217/FMB.15.57
关键词: Serial dilution 、 Antibacterial activity 、 Microorganism 、 Multiple drug resistance 、 Antimicrobial 、 Chemistry 、 Microbiology 、 Resistant bacteria 、 Bone substitute 、 Bioactive glass S53P4
摘要: Aims: This study aimed to evaluate the antimicrobial activity of two different formulations bioglass BAG-S53P4 against multiresistant microorganisms involved in bone infections, and capability select for resistance. Methods: Antibacterial was evaluated by means killing curves. The ability resistant bacteria subculturing serial dilutions bioglass. Scanning electron microscope acquisitions were conducted bioglass-induced morphology changes. Results: display a high do not seem microscopy analysis showed cell shrinkage membrane damage after exposure Conclusions: has significant potential as substitute treatment infections caused microorganisms.
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