Contrast-Enhanced Ultrasonography of the Uterus During Normal Equine Pregnancy: Preliminary Report in Two Mares

作者: Francesca Freccero , Marco Baron Toaldo , Carolina Castagnetti , Mario Cipone , Alessia Diana

DOI: 10.1016/J.JEVS.2017.02.011

关键词: FetusPlacentaObstetricsUterusNuclear medicineGross examinationContrast mediumPregnancyPerfusionContrast-enhanced ultrasoundMedicine

摘要: Abstract There are no reports on use of contrast-enhanced ultrasonography (CEUS) in equine obstetrics. The aim this study was to evaluate feasibility and safety CEUS as a technique for monitoring quantifying perfusion the uterus throughout normal pregnancy mares. Two pregnant Standardbred healthy mares underwent real-time two-dimensional ultrasonography, Doppler ultrasound, uteroplacental unit day 40, at 90–100 days, then every 30 days, 10 days during last month pregnancy. Foeto-placental well-being particular fetal heart rate an index stress were monitored, main uterine arteries diameter parameter resistance (RI) measured. Contrast-enhanced quantitative variables, peak intensity, arrival time, time from injection, initial rise No contrast medium observed fetus, umbilical vein, allantochorionic layer unit. Neonatal foals clinically normal. Placenta postpartum gross examination both A progressive bilateral increase noticed RI reduced early first half remained relatively unchanged until delivery. Contrast enhancement satisfactory all CEUS. Peak intensity showed overall fivefold 10-fold mare no. 1 2, respectively. discrete trend change other variables. is feasible seems safe microperfusion

参考文章(41)
Ousey Jc, Rossdale Pd, Ricketts Sw, Silver M, Jeffers-Lo J, McGladdery Aj, Cottrill Cm, The placenta as a determinant of fetal well-being in normal and abnormal equine pregnancies. Journal of reproduction and fertility. ,vol. 44, pp. 591- 601 ,(1991)
J. C. OUSEY, M. KÖLLING, R. NEWTON, M. WRIGHT, W. R. ALLEN, Uterine haemodynamics in young and aged pregnant mares measured using Doppler ultrasonography Equine Veterinary Journal. ,vol. 44, pp. 15- 21 ,(2012) , 10.1111/J.2042-3306.2011.00446.X
ALESSIA DIANA, SWAN SPECCHI, MARCO BARON TOALDO, ROBERTO CHIOCCHETTI, ANDREA LAGHI, MARIO CIPONE, CONTRAST‐ENHANCED ULTRASONOGRAPHY OF THE SMALL BOWEL IN HEALTHY CATS Veterinary Radiology & Ultrasound. ,vol. 52, pp. 555- 559 ,(2011) , 10.1111/J.1740-8261.2011.01829.X
S. WILSHER, W. R. ALLEN, Factors influencing placental development and function in the mare. Equine Veterinary Journal. ,vol. 44, pp. 113- 119 ,(2012) , 10.1111/J.2042-3306.2011.00452.X
C.J. Arthuis, A. Novell, J.-M. Escoffre, F. Patat, A. Bouakaz, F. Perrotin, New insights into uteroplacental perfusion: Quantitative analysis using Doppler and contrast-enhanced ultrasound imaging Placenta. ,vol. 34, pp. 424- 431 ,(2013) , 10.1016/J.PLACENTA.2013.01.019
C. Gomez-Cuetara, J. M. Flores, J. Sanchez, A. Rodriguez, M. A. Sanchez, Histological changes in the uterus during postpartum in the mare. Anatomia Histologia Embryologia. ,vol. 24, pp. 19- 23 ,(1995) , 10.1111/J.1439-0264.1995.TB00004.X
W.H. Barth, D.C. McCurnin, K. Dee Carey, G.D.V. Hankins, Contrast Sonography, Video Densitometry and Intervillous Blood Flow: A Pilot Project Placenta. ,vol. 27, pp. 719- 726 ,(2006) , 10.1016/J.PLACENTA.2005.07.007
Christopher S Keator, Jonathan R Lindner, J Todd Belcik, Cecily V Bishop, Ov D Slayden, None, Contrast-enhanced ultrasound reveals real-time spatial changes in vascular perfusion during early implantation in the macaque uterus. Fertility and Sterility. ,vol. 95, pp. 1316- 1321 ,(2011) , 10.1016/J.FERTNSTERT.2011.01.040
David Cosgrove, Ultrasound contrast agents: An overview European Journal of Radiology. ,vol. 60, pp. 324- 330 ,(2006) , 10.1016/J.EJRAD.2006.06.022