Genetics of nasopharyngeal carcinoma and molecular signaling pathways

摘要: Abstract Nasopharyngeal carcinoma (NPC) is a distinctive type of cancer with considerable geographical and racial distribution. It multifactorial disease associated genetic environmental factors as well Epstein–Barr virus infection. Increased understanding molecular events in NPC development leads to renewed interest personalized treatment the disease. Recent studies have demonstrated that low mutation rate, epigenetic alterations, dysregulation microRNAs long noncoding RNAs. Discovery biomarkers promises better future improving early detection prognosis NPC. This chapter presents genomic landscapes role profile targeted therapy. discusses potential application screening an aim provide using biomarkers. limited documented data on therapy markers, thus more are needed for full integration such into management