Réponses cutanées sympathiques et sclérose en plaques : étude descriptive, prospective et association aux troubles neuropérinéaux

作者: M. Thomas-Pohl , L. Weglinski , M. Salga , C. Blum , P. Manceau

DOI: 10.1016/J.PUROL.2014.06.009

关键词: GynecologySympathetic skin responseMedicine

摘要: Resume But Decrire les reponses cutanees sympathiques (RCS), reflet de l’activite sudoripare mediee par le systeme nerveux sympathique, chez des patients atteints sclerose en plaques (SEP) suivis pour troubles vesicosphincteriens et associer anomalies RCS aux neuroperineaux. Methode Etude monocentrique prospective d’une population SEP, ayant eu scores symptomes (Expanded Disability Status Scale [EDSS], Urinary Symptoms Profile [USP], Neurogenic Bowel Dysfunction [NBD], International Index of Erectile Function [IIEF] Female Sexual [FSFI]) un recueil a la paume, plante pieds au perinee, declenchees stimulation mecanique, avant apres traitement anticholinergique. Resultats Vingt-huit ont ete inclus. Parmi eux, 18 avaient une abolition RCS, respectivement 10, 14 et 17 sur perinee pieds. L’absence n’etait pas reliee ( p  > 0,05) avec duree maladie, EDSS, USP, NBD ou IIEF15. Il existait relation statistiquement significative entre l’abolition genito-sexuels femme  = 0,01). Le anticholinergique aboli 40 % mains 67 % L’abolition etait associee  = 4 × 10 −5 ). Conclusion Chez ces SEP consultant neuroperineaux, plus moitie avaient qui ne semblaient etre associees anorectaux, mais femme. La prise d’anticholinergique faisait frequemment disparaitre paume Niveau preuve 4.

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