作者: Sonia Cheng , Karen Gomez , Omar Serri , Constance Chik , Shereen Ezzat
DOI: 10.1371/JOURNAL.PONE.0127276
关键词: Medicine 、 Diabetes mellitus 、 Internal medicine 、 Comorbidity 、 Cancer 、 Pituitary neoplasm 、 Young adult 、 Oncology 、 Sex factors 、 In patient 、 Acromegaly 、 Endocrinology
摘要: Background The risk and mortality due to cancer in patients with acromegaly have been previously investigated. Although GH/IGF-1 excess provides a probable pathophysiological explanation, the degree of IGF-1 role acromegaly-associated neoplasms diabetes, common comorbidity known association cancer, remains unclear.