Induced Hyperthermia in the Treatment of Cancer

作者: Bert Hildebrandt , Johanna Gellermann , Hanno Riess , Peter Wust

DOI: 10.1007/978-90-481-9704-0_21

关键词: HyperthermiaRadiologyAdjuvant therapySoft tissue sarcomaCancerMedicineMelanomaIn patientChemotherapyLocally advanced

摘要: The term “hyperthermia” summarizes the treatment of malignant diseases by application heat using different techniques. Hyperthermia is usually applied as an adjunct to established modality claiming intratumoral temperatures in range 40–43°C. Several clinical phase-III trials have demonstrated improvements outcome when locoregional hyperthermia added radio- and/or chemotherapy patients with locally advanced or recurrent superficial and pelvic tumors. Further studies revealed a benefit for hyperthermic chemoperfusion adjuvant therapy abdominal malignancies melanoma extremities. Finally, addition whole-body systemic has promising results number recent phase – II studies. This chapter gives summary on research, points out most interesting future developments.

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